All about Lenacapavir, The Breakthrough Drug of 2024 In an unexpected turn events, Science named Lenacapavirn not just the breakthrough drug of 2024, but the breakthrough of 2024 across all domains of science and technology. What is it about this drug? Let’s find out. Lenacapavir represents a novel and promising advancement in the treatment of …
Hemophilia is a rare but serious genetic disorder that impairs the blood’s ability to clot, leading to prolonged bleeding and frequent hemarthroses (joint bleeds). For individuals living with this condition, managing bleeding episodes is paramount to preventing complications such as joint damage and long-term disability. Over the past few years, new treatments have emerged to …
From Pills to Circuits: How Clinical Trials are pushing the frontier of migraine treatment Migraines are more than just headaches. They are complex neurological conditions that affect over one billion people worldwide, characterized by intense, throbbing pain, often accompanied by symptoms like nausea, sensitivity to light and sound, and visual disturbances. While the exact mechanisms …
Aging is an inevitable biological process that affects every living organism. While aging is not a disease, it is accompanied by a decline in physiological functions and an increased risk of chronic illnesses, such as cardiovascular disease, cancer, diabetes, and neurodegenerative disorders. As global life expectancy increases, the need for clinical research focused on aging …
Pulse Field Ablation (PFA) is a revolutionary technique in the field of cardiac electrophysiology, offering a safer and more precise method to treat arrhythmias, particularly atrial fibrillation (AF). By leveraging the principles of electroporation, PFA selectively targets cardiac tissue while sparing surrounding structures. This essay delves into the history of PFA, its current role in …
Stanford Researchers Discover Skin Bacterium as a Revolutionary Topical Vaccine A groundbreaking discovery by Stanford researchers has unveiled a new potential vaccine delivery system using a naturally occurring skin bacterium. This innovative approach could revolutionize how we prevent and treat infectious diseases, offering a needle-free and skin-friendly alternative to traditional vaccination methods. The Science …
Vaccination Via Creams: An Interesting Alternative Read More »
Part 3 In this series, we have been taking a deep dive into Anti-Drug Antibodies, ranging from the history of its discovery and its biological foundations. In this installment, the clinical methods of detecting and measuring ADA levels will be discussed in some detail. Analytical Techniques of ADA ELISA-based Methods Bridging ELISA serves as …
ANTI-DRUG ANTIBODIES (ADAs): DETECTION AND MEASUREMENT METHODOLOGIES Read More »
Part 2 In the previous article in this series on ADAs, we discussed the historical background of antibody discovery and research. We also discussed the significance of ADAs in modern drug development. In this instalment, we will be getting into the weeds of immunology and how ADAs play a role in it. So, tighten your …
Part 1 Anti-Drug Antibody Analysis is widespread in Clinical Trials across all phases and in the next series of articles, we will introduce you to what they are, their functions, roles, historical development of ADA discovery and the future of research with ADAs. Anti-drug antibodies (ADAs) are immunoglobulins (these are protein substances that help defend …
Introduction Neurodegenerative diseases encompass a group of disorders characterized by neuronal loss and progressive degeneration of the nervous system, posing a significant global health challenge with increasing incidence rates (Sumera et al., 2023). These diseases, such as Alzheimer’s, Parkinson’s, Huntington’s, amyotrophic lateral sclerosis (ALS), and Multiple sclerosis, are multifactorial conditions often associated with gene mutations …
