Stanford Researchers Discover Skin Bacterium as a Revolutionary Topical Vaccine A groundbreaking discovery by Stanford researchers has unveiled a new potential vaccine delivery system using a naturally occurring skin bacterium. This innovative approach could revolutionize how we prevent and treat infectious diseases, offering a needle-free and skin-friendly alternative to traditional vaccination methods.   The Science …

Vaccination Via Creams: An Interesting Alternative Read More »

Part 3 In this series, we have been taking a deep dive into Anti-Drug Antibodies, ranging from the history of its discovery and its biological foundations. In this installment, the clinical methods of detecting and measuring ADA levels will be discussed in some detail.   Analytical Techniques of ADA ELISA-based Methods Bridging ELISA serves as …

ANTI-DRUG ANTIBODIES (ADAs): DETECTION AND MEASUREMENT METHODOLOGIES Read More »

Part 2 In the previous article in this series on ADAs, we discussed  the historical background of antibody discovery and research. We also discussed the significance of ADAs in modern drug development. In this instalment, we will be getting into the weeds of immunology and how ADAs play a role in it. So, tighten your …

ANTI-DRUG ANTIBODIES (ADAs) IN IMMUNOLOGY Read More »

Part 1 Anti-Drug Antibody Analysis is widespread in Clinical Trials across all phases and in the next series of articles, we will introduce you to what they are, their functions, roles, historical development of ADA discovery and the future of research with ADAs. Anti-drug antibodies (ADAs) are immunoglobulins (these are protein substances that help defend …

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Introduction Neurodegenerative diseases encompass a group of disorders characterized by neuronal loss and progressive degeneration of the nervous system, posing a significant global health challenge with increasing incidence rates (Sumera et al., 2023). These diseases, such as Alzheimer’s, Parkinson’s, Huntington’s, amyotrophic lateral sclerosis (ALS), and Multiple sclerosis, are multifactorial conditions often associated with gene mutations …

NEURODEGENERATIVE CLINICAL RESEARCH IN 2024: ALS, DEMENTIA, MYSTHANIA GRAVIS, DEMENTIA, ALZHEIMER’S, HUTTINGTON Read More »

Introduction  Overview of the significance of surgical robots. Since hemorrhagic shock and polytrauma are the most common causes of main fatality in conflict, the military needed to provide skilled surgical care based on damage control surgery as soon as possible following major trauma. Surgical robots have come a long way from their use in entertainment …

THE EVOLUTION OF SURGICAL ROBOTS AND IT’S FUTURE IN HUMAN HEALTH Read More »

Clinical trials are becoming increasingly important in society because they provide unbiased evidence about treatment effectiveness and assist in determining their cost-effectiveness. However, they face challenges, including the need for clearer communication of their benefits to the general public. Despite these challenges, clinical trials are critical for evidence-based medicine and healthcare reform, and they must be …

Top 10 Clinical Research Predicted To Shake The Public Read More »

Introduction In medical research and clinical trials data management and analysis are key to treatment efficacy and safety. Clinical Data Management (CDM) and Clinical Data Science (CDS) are two related but distinct fields. While they share the same goal to collect, organize and analyze clinical data they have different approaches, methodologies and outcomes. Knowing the …

Clinical Data Management Versus Clinical Data Science Read More »

Organ growing represents one of the most exciting and transformative areas of biomedical research. This field aims to address the chronic shortage of donor organs and the limitations of current transplantation methods by developing lab-grown organs that can be used for transplantation. The advances in this area promise to revolutionize healthcare by providing personalized, immunocompatible …

Organ Growing Research: Current State and the Future Read More »

DEFINITIONS Real World Evidence (RWE) is the clinical evidence obtained from the analysis of Real World Data (RWD) revealing the possible risks and benefits associated with an investigational product thereby confirming or nullifying the safety and efficacy status of such investigational/medical product. As the name implies Real World Experience uses real world data generated from …

Real World Evidence in Clinical Research Read More »